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MAB<H-S-Amy>M-Tu66C7 IgG

lyophilizate

For further processing only.

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Order information
MAB<H-S-Amy>M-Tu66C7 IgG material number and pack size:
Material Number Pack Size
11543601103 custom fill
Will be supplied as "MAK<H-S-Amy>M-Tu66C7-IgG(BR)SQ". Unit of measure is "g active ingredient".
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Overview
For measurement of acute pancreatitis (pancreatic α-amylase) in human serum and urine selective blocking of salivary α-amylase isoenzyme is achieved in the presence of the pancreatic h-α-amylase.
Qualified for the cobas® platforms.
Immunogen: Human salivary amylase
Spleen donor: Mouse Balb/c
Antibody class: IgG1, kappa
Clone: Tu66C7
Cross reactivity to h-pancreas α-amylase: ≤1 U/gW
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Application
The combination of MAB<H-S-Amy>Tu88E8 and MAB<H-S-Amy>Tu66C7 inhibits the human salivary α-amylase ≥97% while maintaining the activity of the pancreatic h-α-amylase.
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Specification
MAB<H-S-Amy>M-Tu66C7 IgG fraction is purified by chromatography and lyophilized from a solution containing protein (≥20 mg/mL), potassium-phosphate buffer and NaCl. No preservatives are added.
Appearance: White lyophilizate
Solubility: Clear colorless solution in NaCl, 0.9% (c=10 mg/mL)
Protein (Biuret): ≥0.7 mg/mg lyophilizate
Purity (HPLC / Mono Q): ≥90 area%
Function testing (synergetic effects at +37°C):
h salivary amylase + MAB : ≤3% amylase activity
h pancreas amylase + MAB <S-AMY>: ≥98% amylase activity
Stability: At -15 to -25°C within specification range for 24 months. Avoid repeated freezing and thawing.