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α-2,6-Sialyltransferase, recombinant

solution

For life science research only. Not for use in diagnostic procedures.

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Order information
α-2,6-Sialyltransferase, recombinant material number and pack size:
Material Number Pack Size
07012250103 custom fill
Unit of measure is "mg".
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Overview
α-2,6-Sialyltransferase is used for in vitro sialylation of all Galβ1-4GlcNAc units on glycoproteins, such as monoclonal antibodies (MABs).
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Application
α-2,6-Sialyltansferase is used for targeted, in vitro sialylation of glycoproteins, which are not, or not fully sialylated.
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Specification
A generic protocol for sialylation of glycoproteins is available. However, the optimal conditions depend on different factors (e.g., the initial and target glycosylation status of the  glycoprotein) and must be determined by the user.
Molar mass: 40.6 kDa by cDNA
Appearance: clear, colorless to slightly yellowish solution
Composition: 50 mM MES, 200 mM NaCl, pH 6.0 ± 0.1 at RT
Specific activity: ≥400 U/µg
Protein concentration: 5.5 ± 0.5 mg/mL
Purity and identity: ≥90%
Bioburde ≤100 CFU/mL (in evaluation)
Endotoxin ≤10 EU/mg (in evaluation)
No animal-derived material is used in this process.
Stability: At -15°C to -25°C within specification range for 12 months.
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License disclaimer

78:The sale of the Product does not exhaust or grant any rights in third party patents including patents of companies of the F. Hoffmann - La Roche AG group of companies, in particular, for the use of modified antibodies obtained by using the product.