N-Glycosidase A (PNGase A)
For further processing only.
N-Glycosidase A (PNGase A) material number and pack size: Material Number Pack Size 11646583103 custom fill
- Enzyme that cleaves N-glycans.
- Use N-Glycosidase A to cleave all types of asparagine bound N-glycans including high mannose-, hybrid-, biantennary-, triantennary- and tetraantennary complex types, provided that the amino group as well as the carboxyl group are present in peptide linkage. Use N-Glycosidase A also to cleave a single N-acetylglucosamine residue from the peptide.
Appearance: Clear, colorless solution
Activity: ≥50 mU/mL
Specific activity (Bradford): ≥0.5 U/mg protein
Contaminants (expressed as percentage of N-Glycosidase-A activity):
Sialidase (after 17 hours at +37°C): ≤0.1%
Proteases (casein-resorufin, after 17 hours at +37°C): A/17h ≤0.025
Stability: At -15 to -20°C within specification range for 24 months.
78:The sale of the Product does not exhaust or grant any rights in third party patents including patents of companies of the F. Hoffmann - La Roche AG group of companies, in particular, for the use of modified antibodies obtained by using the product.